Koppikar was born in 1976 at Mahim, Mumbai in a Konkani family. She has one younger brother. She graduated in Life Sciences at Ramnarain Ruia College in Mumbai. While at college she appeared in a photoshoot for Indian photographer Gautam Rajadhyaksha. The shoot led to work in advertising as a model, notably for L'Oréal, Rexona, Camay, Tips & Toes and Coca-Cola. Koppikar competed in the 1995 Miss India contest, winning the Miss Talent Crown. Her modelling work gave her an introduction to the film industry and to her first film appearance in the Telugu movie Chandralekha in 1998.

Debut in South India (1998–2001)

The 1997 Hindi film Ek Tha Dil Ek Thi Dhadhkan, directed by Shahrukh Sultan, is often stated to be Koppikar's first film, but there is no evidence the project was ever released. Her career must therefore be said to have begun with the 1998 Telugu film Chandralekha, co-starring alongside Nagarjuna, and directed by Krishna Vamsi, with music by Maestro Sandeep Chowta. She was awarded the Filmfare Best Female Debut Award. Continuing her Tamil film career, Koppikar's second movie was En Swasa Kaatre in 1998, opposite Arvind Swamy, directed by K. S. Ravi, with music by renowned music director A. R. Rahman. 1998 saw a third film, this time a cameo appearance in Praveen Kanth's Jodi, starring Prashanth and Simran.

In 1999, Koppikar alternated between appearances in the Telugu comedy Chandralekha, co-starring Nagarjuna and Ramya Krishnan, directed by Krishna Vamshi; and the Tamil gangland movie Nenjinile, starring Vijay and directed by S. A. Chandrasekhar.

By 2000, Koppikar's sights were on Bollywood, but this did not stop her from appearing in three Kannada films: Hoo Anthiya Uhoo Anthiya with Ramesh and directed by Praveen Naik, with music by Karthik Raja; O Nanna Nalle, starring and directed by Ravichandran; and finally Surya Vamsha, directed by S Narayan and starring Vishnuvardhan in a double role as father and son. Both O Nanna Nalle and Surya Vamsha were box office successes.

After a detour to Mumbai for a brief appearance in Fiza and an item number in Rahul, Koppikar returned to the south in 2001 for Sundar C's Tamil project Kaathal Solla Vanthen. This film however never left the development stage, although a soundtrack of the same name was made available. Koppikar's penultimate South Indian role was in the Telugu comedy Prematho Raa, starring Venkatesh and Simran, and directed by Uday Shankar, and she signed off her South Indian career with the Tamil action movie Narasimha, directed by Thirupathisamy and starring Vijayakanth.

Bollywood (2000–2008)

Taking time out from four Kannada films in 2000, Koppikar appeared alongside Karisma Kapoor and Hrithik Roshan in Khalid Mohamed's Fiza. An item number appearance in Prakash Jha's Rahul completed Koppikar's introduction to Hindi film. Brief returns to South India in 2001 were coupled with Koppikar's proper Bollywood debut in a small supporting role in Rajiv Rai's Pyaar Ishq Aur Mohabbat, starring Arjun Rampal and Sunil Shetty. Koppikar was paired with Shetty in the film. Her next release was K. Raghavendra Rao's urban comedy Aamdani Atthani Kharcha Rupaiyaa, opposite Govinda, Juhi Chawla and Johnny Lever. By 2002, Koppikar appeared to be consigned to support roles until she was asked by Ram Gopal Varma to appear in an item number for his underworld movie Company starring Ajay Devgan, Vivek Oberoi and Manisha Koirala. The number in question was Khallas, choreographed by Ganesh Hegde and the effect on cinema audiences and critics was to leave her with the enduring nickname Khallas Girl. A second notable item number, Ishq Samundar, in Sanjay Gupta's Reservoir Dogs remake Kaante, starring Amitabh Bachchan, Sanjay Dutt and Sunil Shetty, was enough to raise her profile and in the following year she took the Stardust Award for Most Exciting New Face for Khallas.

Koppikar's career produced five films in 2003. In Dil Ka Rishta, directed by Naresh Malhotra, she played opposite Arjun Rampal and Aishwarya Rai, marking Koppikar's second appearance with Rampal. Prawaal Raman's portmanteau film Darna Mana Hai saw her alongside college whipping boy Aftab Shivdasani. Chandraprakash Dwivedi cast her alongside Urmila Matondkar and Manoj Bajpai in the critically acclaimed film Pinjar, which went on to win the National Film Award for Best Feature Film on National Integration. A brief appearance in J. P. Dutta's war movie LOC Kargil paired her opposite Sunil Shetty again. And in Harry Baweja's Qayamat: City Under Threat, she played one of three terrorists fighting off co-stars Ajay Devgan and Sunil Shetty; a role which would bring her a Filmfare nomination in the Best Villain category.

In 2004, Koppikar's films were releasing on average every two months. Both Mani Shankar's science fantasy Rudraksh and Kundan Shah's madcap comedy Ek Se Bhadkhar Ek teamed her next to perennial acting partner Sunil Shetty. In Krishna Cottage, she was cast opposite Sohail Khan for Santram Varma's creepy ghost story. Inteqam, directed by Pankaj Parashar and co-starring Manoj Bajpai, saw her revive the role played by Sharon Stone in the original Hollywood version: Basic Instinct. Another cameo appearance in Kunal Kohli's Hum Tum with Saif Ali Khan and Rani Mukerji could have left a comedy taste to 2004, but this would be the year of street protests following Karan Razdan's controversial Girlfriend, co-starring Amrita Arora and Aashish Chaudhary caught in a lesbian love triangle. The film provoked public poster burning and calls for the film to be banned.

In 2005, she eased up somewhat only releasing four films. Sangeeth Sivan's bawdy comedy Kyaa Kool Hai Hum, with Anupam Kher, Ritesh Deshmukh and Tusshar Kapoor saw her nominated in three separate award ceremonies (IIFA, Zee Cine Award and Star Screen Awards) for best comedy role. Two more comedies saw her make guest appearances: David Dhawan's Salman Khan vehicle Maine Pyaar Kyun Kiya?, and Abbas-Mustan's whodunit, 36 China Town with Akshaye Khanna and Kareena Kapoor. A return to Ram Gopal Varma's Factory saw her alongside Chunky Pandey in Vishram Sawant's gangster flick D: Underworld Badhshah, starring Randeep Hooda.

Farhan Akhtar directed a 2006 remake of the Amitabh Bachchan hit Don: The Chase Begins Again, this time with Shahrukh Khan in the lead. Koppikar was cast as Khan's girlfriend 'Anita'. But Don's tremendous success came in contrast to Koppikar's stuttering career, with a string of films stuck in production or abandoned. Vicky Ranawat's Haseena Smart Sexy and Dangerous crept out towards the end of 2006, but Jagdish A Sharma's murder mystery Gahraee appeared directly on DVD while Hansal Mehta's Raakh and Jahnu Barua's Har Pal were shelved. Ram Gopal Varma's much discussed Shabri, directed by Lalit Marathe -a role which led her to being unrecognised and barred from the film set by security personnel- struggled to attract a distributor.

Koppikar's highest profile film of 2007, Nikhil Advani's multi-starrer Salaam-e-Ishq, saw her sharing limited screen time with Sohail Khan. Later in the year came the haunted love triangle of Ram Gopal Varma's Darling, with Fardeen Khan and Esha Deol. Koppikar's first film release of 2008 was Atul Agnihotri's Hello, based on the best-selling novel One Night @ the Call Center by Chetan Bhagat. This was followed within weeks by Ek Vivaah... Aisa Bhi, a Rajshri Production directed by Khashik Ghatak and co-starring Sonu Sood.

After her wedding (2009–)

Koppikar did not appear in any film in 2009, the year of her wedding with Timmy Narang. She had two films released in 2010: Right Yaaa Wrong by Neeraj Pathak and Manoj Tiwari's Hello Darling. Both films fared poorly at the box office.

Shabri, where she plays a woman gangster of Mumbai, was eventually released in 2011. Her performance was praised but the film only had a limited release and failed to make an impact at the box office. In 2013, she made her Marathi debut in Maat, a film by director Manohar Sarvankar. She played the lead role opposite Sameer Dharmadhikari in a story revolving around an ambitious couple.

She has been announced in a Kannada film, Looti, where she is to play a police officer, as well as in a Hindi movie directed by Ankur Bhatia co-starring Divyendu Sharma.^[16][17]

Between filming Koppikar, like many Bollywood actors, performs in stage music shows. In addition to this she has appeared in two music videos: Patli Kamar by KK for a private album commissioned by Sony in 2001/2002; and Bandish Projekt's Bhor (Satyam Shivam Sundaram) in 2004, choreographed by Bosco-Caesar. In 2006 she appeared onstage in the Indian Idol Grand Final to dance with the two finalists, and 2007 saw her as one of three judges in the celebrity dance competition Nach Baliye3, alongside director David Dhawan and Vaibhavi Merchant. She served as a judge in the Miss Universe 2008 contest, held on 14 July in Vietnam alongside, amongst others, fashion designer Roberto Cavalli and former winner in 2004 Jennifer Hawkins. In August 2009, she presented the new Colors wrestling show 100% De Dana Dan.

She continues to model for fashion designers Anita Dongre and Pria Kataria Puri. In 2007, she became the Indian brand ambassador of the Italian fashion company Police Time and Jewellery.^[18] Koppikar is also a spokesperson for the animal rights organisation PETA^[19] and received the 10th Anniversary Humanitarian Award in December 2009.^[20]

She has a black-belt in Taekwondo.^[21]

Following the advice of numerologists, she has changed the spelling of her name twice, first to Ishaa Koppikar and later to Eesha Koppikhar. However, as of 2015 she has reverted to the original spelling of her name.^[16]

She was involved romantically with actor Inder Kumar for many years.^[22] Leena Mogre and Preity Zinta introduced her to hotelier Timmy Narang,^[22] whom she married on 29 November 2009.^[23]

She gave birth to their daughter Rianna in July 2014.^{[24][25][26][27]}

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