She made her debut in 1972 in A. Vincent's Malayalam movie Theerthayathra with screen name Supriya, followed by Ithu Manushyano? in 1973. In 1974 she made her Tamil debut in K Balachander’s film Aval Oru Thodar Kathai credited as Jayalakshmi. She became a household name with her popular dialogue ‘Fatafat’ (meaning quickly) in the movie. Her notable films include Aval Oru Thodar Kathai, Anthuleni Katha, Aarilirunthu Arubathu Varai and Mullum Malarum. She had co-starred with top actors like Rajinikanth, Kamal Haasan, Krishna, NTR and Chiranjeevi.

She was married to the nephew of M. G. Ramachandran. She committed suicide by hanging in 1980 when she was at the peak of her career.

Tamil

Telugu

1. Iddaru Ammayilu (1972) - Debut film in Telugu
2. Swargam Narakam (1975)
3. Jyothi (1976) - Sashirekha
4. Anthuleni Katha (1976)
5. Bhale Alludu (1977)
6. Korikale Gurralaite (1979)
7. Muttaiduva (1979)
8. Jathara (1980)
9. Ram Robert Rahim (1980)
10. Nyayam Kavali (1981) - Jayalaxmi (Suresh's wife)
11. Tirugu Leni Manishi (1981) - Padma

Malayalam : Credited as Supriya

1. Theerthayathra (1972)... Parvathy - Debut film in Malayalam
2. Ithu Manushyano? (1973)
3. Darsanam (1973)
4. Sreedevi (1977)
5. Prathyaksha Daivam (1978)

Kannada

1. Devara Kannu (1975) - Rekha - Debut film in Kannada
2. Ondu Hennu Aaru Kannu (1980)