Ghosh made her film debut in Sakhar Das's Mohul Bener Sereng, followed by Tista in 2005, Manush Bhut and Dosar in 2006 and Kaal in 2007. In 2008/09 she announced the beginning of her directorial venture with Sama. The film, which dwells on homosexuality, as per her it is based on her own story and the music will be composed by the actor Parambrata Chatterjee. She said, "I was mentally preparing myself to step into direction for a long time," and "I now have the confidence to go ahead with this independent project." She has also been in several television roles, such as Raat Bhor Brishti, Uttaron and Mohona. She will next be seen in a megaserial, Dushaha Bash, based on Taslima Nasreen’s work and deals with the lives of three sisters. She also had a successful stint with comedy in the serial Labonor Sansar, which was telecast on Zee Bangla. She is currently active with a number of serials, among them the major one are Behula as in Hindu Goddess Manasa, Ekhane Aakash Neel, Sindoorkhela, Kiranmala, Debipaksha and Bodhu Kon Alo Laaglo Chokhe all six telecasted on Free-to-Air Channel Star Jalsa

Films

• Kuheli - November 2016
• Tiyasha - Sept 2013
• Necklace 2011
• Hatey Roilo Pistol 2011
• Kaaler Rakhal 2009
• Kaal 2007
• Dosar 2006
• Manush Bhut 2006
• Tista 2005
• Mahulbonir Sereng (debut movie) 2004

Television

• Bandhobi
• Behula
• Bodhu Kon Alo Laaglo Chokhe
• Kiranmala
• Debipakshya
• Sindoorkhela

• 2005: BFJA-Most Promising Actress Award : for Mahulbonir Sereng