Bindu was born to film producer Nanubhai Desai and his wife Jyotsna at a small village called Hanuman Bhagda in the district of Valsad in the Western Indian state of Gujarat. Bindu's road to success was not an easy one. Her father died when she was 13. Being the eldest daughter, the burden of earning money fell on her shoulders.

Bindu made her debut in Anpadh (1962), playing a young college graduate. She was 21 at the time.

Bindu had early successes with Ittefaq and Do Raaste in 1969. From here she went on to write her success story with Shakti Samanta's Kati Patang (1970), where she had a sizzling cabaret dance, "Mera Naam Shabnam" to her credit; a number which is even today remembered as one of the highlights of the film.

Bindu's mesmerising performances in 1974 as a seductress in Imtihan, and as a nymphomaniac in Hawas, left audiences asking for more. With a string of hits behind her, she successfully managed to break out of the myth that married actresses usually do not go to become sex symbols, especially in the Hindi film industry. She is the third point in the 'holy trinity' of item number queens. Along with Helen and Aruna Irani, Bindu defined the Bollywood 'cabaret' dance number and the role of the 'Vamp'.^[4]

Her acting ability was seen in films like Hrishikesh Mukherjee's films Arjun Pandit and Abhimaan, where she won raves for playing a very sympathetic character. She proved to be just as convincing as the crippled woman in Chaitali and as the deglamorised role of wife to Ashok Kumar, in Arjun Pandit. She played the villain's moll in Zanjeer and became famous as Mona Darling.

An impending pregnancy, followed by a miscarriage^{[according to whom?]}, brought about a lull in her career and on the advice of her doctors she had to end her stint as the glamorous 'vamp' – dancing and all. However, she did not stay away for long and returned to the silver screen with character roles – Hero, Biwi Ho To Aisi and Kishen Kanhaiya and with many other such movies she managed to re-establish herself as the unmerciful and cruel mother-in-law, or the cynical aunt.

In the later stages of her career, she made fewer on-screen appearances, like the ones in Shola Aur Shabnam, which highlighted her comic side, and followed with other light and funny performances in Hum Aapke Hain Koun..!, Main Hoon Na, and Om Shanti Om.

Bindu married her childhood sweetheart and next door neighbour Champaklal Zaveri. She has no children. She currently resides in Koregaon Park, Pune. She's a member of Derby and often spotted at the race course at Pune.

• Nominated – Filmfare Award for Best Supporting Actress – Ittefaq (1969)
• Nominated – Filmfare Award for Best Supporting Actress – Do Raaste (1970)
• Nominated – Filmfare Award for Best Supporting Actress – Dastaan (1972)
• Nominated – Filmfare Award for Best Supporting Actress – Abhimaan (1973)
• Nominated – Filmfare Award for Best Supporting Actress – Hawas (1974)
• Nominated – Filmfare Award for Best Supporting Actress – Imtihan (1974)
• Nominated – Filmfare Award for Best Supporting Actress – Arjun Pandit (1976)

• Anpadh (1962) ... Kiran
• Aurat (1967)
• Aya Sawan Jhoom Ke (1969)
• Doli (1969)
• Do Raaste (1969)
• Ittefaq (1969)
• Nateeja (1969)
• Kati Patang (1970)
• Amar Prem (1971)
• Preet Ki Dori (1971)
• Dushman (1971) ... Special Appearance
• Haseeno Ka Devta (1971)
• Dastaan (1972)
• Dil Ka Raaja (1972)
• Ek Bechara (1972)
• Garam Masala (1972)
• Raja Jani (1972) ... Special Appearance
• Mere Jeevan Saathi... (1972)
• Abhimaan (1973)
• Gaai Aur Gori (1973)
• Dharma (1973)
• Joshila (1973)
• Zanjeer (1973)
• Hawas (1974)
• Free Love (1974)
• Imtihan (1974)
• Pagli (1974)
• Prem Nagar (1974)
• Bangaarada Panjara (1974 Kannada film) ... Reshma
• Chaitali (1975)
• Dafa 302 (1975)
• Jaggu (1975)
• Sewak (1975)
• Dhoti Lota Aur Chowpatty (1975)... Dancer
• Arjun Pandit (1976)
• Shankar Shambhu (1976)... Munni Bai
• Shankar Dada (1976)... Bindya
• Shaque (1976)... Rosita
• Dus Numbri (1976)
• Nehle Pe Dehla (1976)
• Thief of Baghdad (1977)
• Chakkar Pe Chakkar (1977)
• Chala Murari Hero Banne (1977)
• Chalta Purza (1977)
• Maha Badmaas (1977)
• Bandie (1978)
• Chor Ho To Aisa (1978)
• Des Pardes (1978) ... Sylvia
• Ganga Ki Saugandh (1978)
• Besharam (1978) ... Manju
• Jalan (1978)
• Trishna (1978)
• Phandebaaz (1978)
• Rahu Ketu (1978)
• Ram Kasam (1978)
• Amar Deep (1979) ... Asha
• Nallathoru Kudumbam (1979 Tamil film)... Dancer in One and two cha cha song
• Inspector Eagle (1979)
• Allaudinaum Arputha Vilakkum (1979 Tamil–Malayalam bilingual)... Dancer in a song
• Khandaan (1979) ... Nanda V. Srivastav
• Sarkari Mehmaan (1979)
• Agreement (1980)
• Jwalamukhi (1980)
• Shaan (1980) ... Special Appearance
• Laawaris (1981)
• Naseeb (1981) ... Special Appearance
• Prem Rog (1982)
• Hero (1983) ... Jamuna
• Paisa Yeh Paisa (1985)
• Karma (1986)
• Hifazat (1987)
• Biwi Ho To Aisi(1988)
• Kishen Kanhaiya (1990)
• Shola Aur Shabnam (1992)
• Honeymoon (1992 film) (1992)
• Aankhen (1993)
• Aasoo Bane Angaarey (1993)
• Roop Ki Rani Choron Ka Raja (1993)
• Hum Aapke Hain Koun..!(1994)
• Judwaa (1997)
• Ehsaas is Tarah (1998)
• Aunty No.1 (1998)
• Banarasi Babu (1998)
• Jaanam Samjha Karo (1999)
• Sooryavansham (1999)
• Mere Yaar Ki Shaadi Hai (2002)
• Main Hoon Na (2004)
• Om Shanti Om (2007)
• Mehbooba (2008)