Sikander Bakht was born in Delhi, India in 1918. He attended the Anglo Arabic Senior Secondary School, Delhi and completed his Bachelor of Science from the Anglo-Arabic College (now known as Zakir Husain College) in Delhi. During his school and college days he was a keen hockey player and represented Delhi University and Delhi in various tournaments. He also played and captained the Independents Hockey Club. He once said he is member of BJP and always maintained that India is land of secularism and supported the ethos of India.

In 1952 Bakht was elected to the Municipal Corporation of Delhi as a Congress candidate. In 1968 he was elected as the Chairman of Delhi Electric Supply Undertaking. In 1969 the Congress party split and Bakht stayed with Congress (Organisation). Bakht was then elected to The Metropolitan Council of Delhi as a Congress (O) candidate. On 25 June 1975 Emergency was declared by Prime Minister Indira Gandhi, Bakht along with other opposition leaders was imprisoned on 25 June 1975. He was lodged in The Rohtak Jail until his release in December 1976. Prime Minister Indira Gandhi ordered General Elections in March 1977. As soon as the opposition leaders were released, they merged all opposition parties to form The Janta Party.

In March 1977 Bakht was elected to the Lok Sabha (the lower house of Indian Parliament) as a Janata Party candidate, from Chandni Chowk in New Delhi. Morarji Desai was appointed Prime Minister and he appointed Bakht as a Cabinet Minister for Works, Housing, Supply and Rehabilitation. He served in this capacity till July 1979.

In 1980 the Janta Party split and Bakht opted to be with the Bharatiya Janata Party (BJP). He was appointed as General Secretary of BJP. In 1984 he was made the Vice President of BJP.

In 1990 Bakht was elected to the Rajya Sabha (the upper house of the Indian Parliament)from Madhya Pradesh. In 1992 he became the Leader of Opposition in the Rajya Sabha. (The Leader of Opposition is equivalent to Cabinet Minister's post.) On 10 April 1996 he was reelected from Madhya Pradesh to the Rajya Sabha.

In May 1996, Atal Bihari Vajpayee offered Bakht the post of Minister of Urban Affairs when he formed his government. Bakht, however, demanded a higher post, and on 24 May he was given the additional post of Minister of Foreign Affairs. The Vajpayee Government lasted only 13 days. Bakht was Foreign Minister for little more than a week, as he was forced to resign when Vajpayee's government collapsed on 1 June 1996. After the collapse of the Vajpayee government, Bakht became the Leader of the Opposition in the Rajya Sabha once again.

In 1998 Vajpayee was again appointed Prime Minister and Bakht was appointed Industry Minister, a post he held until 2002. In addition, he was appointed as the Leader of the House in Rajya Sabha. After serving an entire term as Industries Minister, Bakht retired from active politics and was appointed as the Governor of Kerala in 2002.

In 2000 Bakht was awarded the Padma Vibhushan. This is the second highest Indian civilian award. The two other persons from the BJP who have been awarded the Padma Vibhushan are Atal Behari Vajpayee and Lal Krishna Advani. Atal Behari Vajpayee has since been awarded Bharat Ratna, the highest civilian award of India.

Bakht finished his term in Rajya Sabha on 9 April 2002. 9 days later, Bakht was sworn in as Governor of Kerala, succeeding Sukhdev Singh Kang. At the age of 83 years, 237 days, he was the oldest Governor of Kerala state. He was highly popular and served in this post until his death. Bakht died in the Medical College Hospital in Kerala's capital city Thiruvananthapuram on 23 February 2004, from complications of intestinal surgery which was performed on 19 February. He was the first Governor who died in office. He was replaced two days later by Karnataka governor T. N. Chaturvedi. There was concern, particularly among BJP members, that Bakht might have died because of medical negligence, but nothing was proven. Chief Minister A.