Saeed Anwar was born on 6 September 1968 in Karachi. In 1973, he shifted with his family to Canada and came back to Karachi in 1977. Anwar went to high school at Government Degree Science College, Malir Cantt and went to university at NED University of Engineering and Technology, Karachi. He graduated from NED in 1989 majoring in Computer System Engineering. He was planning to go to the United States for his Master's studies before becoming a professional Test cricketer. His father, a businessman by profession, played cricket at club level whereas his brother, Jawed Anwar, represented Lahore Under-19 cricket team.

Anwar married his cousin, Lubna, a doctor by profession, in March 1996. He faced a personal tragedy in 2001 when his daughter, Bismah, died after a prolonged illness. As a result, he turned religious and starting preaching Islam across Pakistan with the Tablighi Jamaat. He made his return to cricket after a long hiatus and was one of the most consistent Pakistani batsmen in the 2003 World Cup. However upon his return, he lost his previous touch and could not perform as he did before. He was criticized for the loss of form which led to his retirement from cricket soon. "I retired because I felt unwanted", he said. During his career, he was an elegant batsman and played particularly well on the off side, his trademark flick being a sure shot feature in almost all of his innings. He led the funeral prayers for his former teammate Wasim Akram's spouse, Huma Akram, in Lahore. He is also believed to be instrumental in Saad's conversion to Islam in 2005. Saad was the only Hindu in the Pakistan Domestic Galli cricket league till then and was said to be influenced by Anwar and the Tablighi Jamaat.